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Updated: Jul 16, 2026

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Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
Long-term outcomes after gastric bypass.
Sarah White1, Emma Brooks, Lydia Jurikova
1Wakefield Gastroenterology Centre, Wellington, New Zealand.
Obesity Surgery
|April 2, 2005
Summary
Long-term gastric bypass surgery outcomes show sustained weight loss and significant improvement in obesity-related conditions like hypertension and type 2 diabetes. These positive results demonstrate the lasting benefits of bariatric surgery for severely obese patients.
Area of Science:
- Bariatric Surgery
- Obesity Medicine
- Metabolic Surgery
Background:
- Limited data exists on the long-term efficacy of gastric bypass surgery.
- Understanding long-term outcomes is crucial for patient selection and managing expectations.
Purpose of the Study:
- To evaluate the long-term outcomes of gastric bypass surgery.
- To assess sustained weight loss and resolution of comorbidities after gastric bypass.
Main Methods:
- A retrospective study of 342 severely obese patients undergoing gastric bypass by a single surgeon.
- Data collected via a computerized database, mailed questionnaires, and blood tests for long-term follow-up (0-14 years).
Main Results:
- Sustained significant weight loss observed up to 10 years post-surgery (e.g., 75% excess weight loss at 10 years).
- High rates of comorbidity improvement: 87% hypertension cure/improvement, 95% type 2 diabetes cure/improvement, and 72% dyslipidemia cure/improvement.
- Excellent safety profile with no 30-day mortality and low rates of severe complications.
Conclusions:
- Gastric bypass surgery provides excellent and durable weight loss.
- Long-term follow-up confirms sustained resolution or improvement of major comorbidities, including hypertension, type 2 diabetes, and dyslipidemia.
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