Chromosomal replication and the cell membrane
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Updated: Aug 18, 2026

Chromosome Replicating Timing Combined with Fluorescent In situ Hybridization
Published on: December 10, 2012
Kelly Boeneman1, Elliott Crooke
1Department of Biochemistry, Georgetown University Medical Center, 3900 Reservoir Road, Basic Science Building, Washington DC, 20007, USA.
Abstract:
The importance of the cell membrane in bacterial chromosomal replication continues to emerge. Recent advances include better definition of the biochemical interaction between membrane acidic phospholipids and the replication initiator, DnaA protein, the physiological impact that an altered membrane lipid composition has on chromosomal replication and the identification and characterization of recently identified membrane-associated proteins that regulate replication and participate in chromosomal segregation.
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