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Updated: Aug 18, 2026

Acupoint Application as a Traditional Chinese Medicine Treatment for Fatigue Associated with Chronic Obstructive Pulmonary Disease
Published on: September 5, 2025
Predictors of outcome following treatment for chronic fatigue
Lucy Darbishire1, Paul Seed, Leone Ridsdale
1Department of General Practice and Primary Care, Guy's, King's and St Thomas' School ol of Medicine, 5 Lambeth Walk, London, SE11 6SP, UK. lucy.clark@kcl.ac.uk
Abstract:
We explored the role of baseline characteristics of 105 patients who presented with fatigue in primary care in determining outcome following either graded exercise or cognitive-behavioural therapy. Meeting the criteria for chronic fatigue syndrome was the most powerful predictor of poor outcome and this negative effect was enhanced by greater functional impairment or greater perceived negative consequences, but was not further enhanced by both.
