Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Evaluating MRI as a technique for visualizing the neurocentral junction.

Talib Rajwani1, Keith M Bagnall, Robert Lambert

  • 1Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Alberta, Canada.

Spine
|April 2, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Breaking barriers in rare disease research: The RARE-X Open Science Data Challenge as a model for collaborative innovation and community partnership.

HGG advances·2025
Same author

Subacute distal radio-ulnar joint subluxation after a distal radius fracture.

The Journal of hand surgery, European volume·2025
Same author

Accuracy of the diagnosis of pneumonia in Canadian pediatric emergency departments: A prospective cohort study.

PloS one·2024
Same author

Machine learning hypothesis-generation for patient stratification and target discovery in rare disease: our experience with Open Science in ALS.

Frontiers in computational neuroscience·2024
Same author

PROPIONATE AND CYCLOHEXIMIDE REVERSIBLY BLOCK PROGESTERONE INDUCED CALCIUM SURGE IN AMBYSTOMA MEXICANUM OOCYTES.

Development, growth & differentiation·2023
Same author

UNCOUPLING OF OOCYTE-FOLLICLE CELLS TRIGGERS REINITIATION OF MEIOSIS IN AMPHIBIAN OOCYTES.

Development, growth & differentiation·2023

Magnetic resonance imaging (MRI) accurately determines neurocentral junction (NCJ) cartilage presence. This imaging method is reliable for assessing NCJ closure age, despite some directional over/underestimations during development.

Area of Science:

  • Orthopedics
  • Radiology
  • Developmental Biology

Background:

  • The neurocentral junction (NCJ) is implicated in adolescent idiopathic scoliosis due to disparate growth.
  • Anatomic studies suggest NCJ closure before age 10, contrasting with recent MRI findings indicating closure in adolescence.

Purpose of the Study:

  • To ascertain the composition of MRI scans of the NCJ.
  • To investigate the discrepancy in NCJ closure ages between anatomic and imaging studies.

Main Methods:

  • 114 porcine NCJs were imaged using MRI.
  • MRI data were correlated with gross anatomic and histologic sections at identical positions.

Main Results:

  • MRI accurately represented NCJ cartilage presence/absence.

Related Experiment Videos

  • MRI overestimated anteroposterior width and underestimated medial-lateral closure extent of the NCJ during development.

    • Conclusions:

    • MRI reliably determines NCJ cartilage presence and absence.
    • Despite some directional inaccuracies, MRI is a reliable method for determining NCJ closure age.
    • Further research into the asymmetric growth hypothesis for scoliosis is warranted.