Related Experiment Video

Updated: Aug 11, 2026

Intracortical Inhibition Within the Primary Motor Cortex Can Be Modulated by Changing the Focus of Attention
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Intracortical Inhibition Within the Primary Motor Cortex Can Be Modulated by Changing the Focus of Attention

Published on: September 11, 2017

Cortical inhibitory neurons and schizophrenia

David A Lewis1, Takanori Hashimoto, David W Volk

  • 1Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA. lewisda@upmc.edu

Nature Reviews. Neuroscience
|April 2, 2005
PubMed
Summary

Schizophrenia impairs working memory due to reduced GABA synthesis in the brain. Targeting TrkB receptor signaling may restore neuronal activity and improve cognitive function in patients.

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