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Published on: November 3, 2008
Model analysis of enzyme monolayer- and bilayer-modified electrodes: the transient response
T Tatsuma1, T Watanabe, Y Okawa
1Institute of Industrial Science, University of Tokyo, Japan.
Abstract:
The transient responses of enzyme monolayer- and bilayer-modified electrodes were theoretically analyzed. The response was numerically simulated with parameters used in the foregoing paper. The transient process consists of three elementary steps: enzymatic reaction step, substrate and mediator consumption step, and charge-carrying mediator accumulation step. Contributions of the parameters to these elementary steps and the overall response were examined. Experimental observations are successfully interpreted in terms of the theoretical results.
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