Related Experiment Video
Updated: Aug 10, 2026

Evaluation of Intracellular Location of Reactive Oxygen Species in Solea Senegalensis Spermatozoa
Published on: March 11, 2018
[On the significance of RNA in human sperm]
1Department of Obstetrics and Gynecology, Center for Molecular Medicine and Genetics, Institute for Scientific Computing, Wayne State University School of Medicine, 275 E. Hancock, Detroit, MI 48201, USA. steve@compbio.med.wayne.edu
Abstract:
Our understanding of the molecular complexities of human spermatozoa continues to be rather rudimentary. This includes the unique packaging and structure of the sperm genome along with its paternally derived RNAs in preparation for their delivery to the egg. Both highlight the inadequacy in our understanding of how these genetic factors contribute to a healthy child. As a means to address this deficiency it was recently shown that human spermatozoal RNA isolated from the ejaculate can be used to transcriptionally profile the male gamete. It is fully expected that a genetic fingerprint characteristic of the normal fertile spermatozoon can be identified and that deviations from this profile can be detected.
Related Concept Videos
Types of RNA
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...
Spermatogenesis
RNA Stability
RNA Stability
Ribosomal RNA Synthesis
Ribosome biogenesis begins with the synthesis of 5S and 45S pre-rRNAs by distinct RNA polymerases. The primary transcripts are extensively processed and modified before they are bound and folded by ribosomal proteins and assembly factors,...
Types of RNA
RNA Performs Diverse...

