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Updated: Jul 29, 2026
Primary Culture of Human Vestibular Schwannomas
Published on: July 20, 2014
Surgery of vestibular schwannomas: an institutional experience
Vijendra K Jain1, Naveen Mehrotra, Rabi Narayan Sahu
1Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226-014, India. vkjain@sgpgi.ac.in
Aims:
To report management results of vestibular schwannomas (VS) treated surgically in our institute, with particular reference to completeness of tumor excision, facial nerve and hearing preservation and complications of surgery.
Study Design And Settings:
Retrospective study of 259 patients treated during the years 1988 to 2002.
Materials And Methods:
The facial nerve function and hearing assessment was done according to House-Brackmann [HB] grading and pure tone audiometry (PTA) respectively. All patients were operated by retro-mastoid sub-occipital approach.
Results:
Most patients had large tumors and had no useful hearing (90%), had disabling cerebellar ataxia (88%) and presented with features of raised intra-cranial pressure (45%). Large sized tumors were in 41.3% and giant sized tumors were in 56% cases. Complete tumor excision was carried out in 96.5% and anatomical preservation of facial nerve was achieved in 79.2% cases. Hearing preservation was achieved in 8 patients. Cerebrospinal fluid leak with or without meningitis and transient lower cranial nerve paresis were common complications. The mortality was 6%.
Conclusions:
With experience, complete tumor excision with good facial nerve preservation can be achieved in large tumors. Hearing preservation is difficult in bigger tumors. Prevention and control of infection was a major concern.
