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Published on: April 21, 2014
Rosai-Dorfman disease mimicking a sphenoid wing meningioma
Manish S Sharma1, Michelle De Padua, Ajaya N Jha
1Department of Surgical Neurology, The Neurosciences Center, The Indraprastha Apollo Hospital, Sarita Vihar, New Delhi 110-044, India.
Abstract:
A 40-year-old male presented with a single generalized tonic-clonic seizure. MRI revealed an enhancing, dural-based, left lateral sphenoid wing lesion suggestive of a meningioma. At microsurgical excision, the lesion was firm and relatively avascular. The histopathological report revealed S-100 positive histiocytic proliferation with lymphophagocytosis (emperipolesis) characteristic of the Rosai-Dorfman disease. The case and its management are discussed.
