Related Experiment Video

Updated: Aug 10, 2026

Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury
09:16

Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury

Published on: June 21, 2019

Vertex extradural hematoma in association with Paget's disease of the skull

V G Ramesh1, K Deiveegan, V Soundappan

  • 1Institute of Neurology, Madras Medical College and Govt. General Hospital, Chennai 600-003, India. drvgramesh@hotmail.com

Neurology India
|April 5, 2005
PubMed

Insights

This study reports a rare case of extradural hematoma in a patient with Paget's disease of the skull. The hematoma, located at the vertex, formed due to oozing from the diseased skull, not a fracture.

Area of Science:

  • Neurology
  • Neurosurgery
  • Medical Imaging

Background:

  • Paget's disease of the skull can lead to neurological issues like basilar invagination and cranial neuropathies.
  • Extradural hematomas are uncommon complications of Paget's disease of the skull.

Observation:

  • A 48-year-old man with Paget's disease of the skull presented with headache and limb weakness after a fall.
  • CT scans revealed a vertex extradural hematoma without skull fracture or superior sagittal sinus injury.
  • Intraoperative findings included diffuse oozing from the inner table of the skull.

Findings:

  • The extradural hematoma was successfully evacuated, but the patient experienced deterioration due to brain swelling.
  • A second surgery to excise diseased skull and evacuate a hematoma recurrence led to complete recovery.
  • This case highlights vertex extradural hematoma in Paget's disease of the skull, likely caused by increased vascularity and oozing.

Implications:

  • This case expands the understanding of potential neurological complications associated with Paget's disease of the skull.
  • It underscores the importance of considering unusual etiologies for extradural hematomas, even in the absence of trauma.
  • The findings suggest that increased skull vascularity in Paget's disease can precipitate bleeding and hematoma formation.

More Related Videos

Accessing the Porcine Brain via High-Speed Pneumatic Drill Craniectomy04:26

Accessing the Porcine Brain via High-Speed Pneumatic Drill Craniectomy

Published on: July 5, 2024

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device04:19

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device

Published on: November 8, 2024

Related Concept Videos

Cranial Bones: Superior and Posterior View01:14

Cranial Bones: Superior and Posterior View

The superior view of the cranium shows the frontal and paired parietal bones.
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...
Cerebral Edema ll: Pathophysiology01:22

Cerebral Edema ll: Pathophysiology

Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...