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Updated: Aug 18, 2026

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Bilateral idiopathic multifocal retinal pigment epithelium detachments in otherwise healthy middle-aged adults: a
J Donald M Gass1, Susan B Bressler, Levent Akduman
1Department of Ophthalmology, Vanderbilt University Medical School, Nashville, Tennessee 37232-8808, USA.
Purpose:
To present the results of a clinicopathologic study of patients with bilateral idiopathic multifocal serous retinal pigment epithelial detachments (RPEDs).
Method:
Retrospective review of the medical records of three middle-aged patients with innumerable RPEDs. The eye of one patient was available for histopathologic examination.
Results:
The presence of multiple serous RPEDs was verified with fluorescein angiography and optical coherence tomography in two patients and by histopathologic examination of one eye of a third patient, who developed a submacular hematoma and vitreous hemorrhage caused by a focal area of choroidal neovascularization.
Conclusions:
No cause for the multifocal serous RPEDs was found.
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