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Updated: Aug 18, 2026

The Immediate Partial Removal of Cumulus-Oocyte Complexes: A Refined Approach for Rapid Observation of In Vitro Fertilization
Published on: October 18, 2024
Intracytoplasmic sperm injection after total conventional in-vitro fertilization failure
Zouhair O Amarin1, Basil R Obeidat, Abdulrahim A Rouzi
1Department of Obstetrics and Gynecology, Jordan University of Science and Technology, Irbid, Jordan. zoamarin@hotmail.com
Objective:
This study assessed the value of delayed intracytoplasmic sperm injection after failure of initial in-vitro fertilization in patients with normal seminology.
Methods:
A case series analysis was conducted on 82 couples who underwent delayed intracytoplasmic sperm injection after failure of initial in-vitro fertilization at Fakeeh Hospital, Jeddah, Kingdom of Saudi Arabia between January 1995 and January 2001.
Results:
Seventy-eight couples had 616 unfertilized metaphase II mature oocytes after initial in-vitro fertilization. Second day "rescue" reinsemination by intracytoplasmic sperm injection (ICSI) resulted in 174 embryos that were suitable for transfer. This resulted in 4 clinical pregnancies (5.1% per started rescue ICSI cycle).
Conclusion:
The limited success rate in this study provides confirmatory data that rescue ICSI is not an efficient adjuvant laboratory procedure.
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