Related Experiment Video
Updated: Aug 10, 2026

High-throughput Assay to Phenotype Salmonella enterica Typhimurium Association, Invasion, and Replication in Macrophages
Published on: August 11, 2014
Association of high fever and short bacterial excretion after salmonellosis
A S el-Radhi1, T Rostila, T Vesikari
1Infectious Diseases Teaching Unit, University of Helsinki, Finland.
Insights
Fever may favorably impact Salmonella excretion duration in children. Higher fevers (≥40°C) correlated with shorter bacterial shedding periods, suggesting a positive prognostic influence.
Area of Science:
- Pediatrics
- Infectious Diseases
- Microbiology
Background:
- Salmonella gastroenteritis is a common childhood illness.
- Convalescent bacterial excretion is a key concern in managing Salmonella infections.
- Factors influencing the duration of Salmonella shedding require further investigation.
Purpose of the Study:
- To investigate factors affecting the length of convalescent Salmonella bacterial excretion in children.
- To determine the prognostic influence of fever on Salmonella excretion duration.
Main Methods:
- A cohort of 102 children diagnosed with Salmonella gastroenteritis was studied.
- Data on fever severity and duration of bacterial excretion were collected and analyzed.
- Statistical correlation was used to assess the relationship between fever and excretion length.
Main Results:
- A significant correlation was observed between the degree of fever and the duration of bacterial excretion.
- Children with higher fevers (≥40°C) exhibited the shortest excretion periods.
- Children without fever showed the longest bacterial excretion durations.
Conclusions:
- Fever appears to have a favorable prognostic influence on the duration of Salmonella excretion in children.
- Monitoring fever may provide insights into the expected course of Salmonella shedding.
- Further research could explore the mechanisms behind fever's effect on Salmonella excretion.
Abstract:
One hundred and two children with salmonella gastroenteritis were studied for factors affecting the length of convalescent bacterial excretion. There was a significant correlation between degree of fever and duration of excretion: a fever of greater than or equal to 40 degrees C had the shortest and no fever the longest duration of excretion. Fever therefore appears to have a favourable prognostic influence on the length of salmonella excretion.
Related Concept Videos
Increased Body Temperature
Methods of reducing fever
Pharmacological Methods of Reducing Fever:
Reservoir of Infection
Bacterial Meningitis
Bacterial Gastroenteritis
Cholera

