Association of high fever and short bacterial excretion after salmonellosis

A S el-Radhi1, T Rostila, T Vesikari

  • 1Infectious Diseases Teaching Unit, University of Helsinki, Finland.

Insights

Fever may favorably impact Salmonella excretion duration in children. Higher fevers (≥40°C) correlated with shorter bacterial shedding periods, suggesting a positive prognostic influence.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Microbiology

Background:

  • Salmonella gastroenteritis is a common childhood illness.
  • Convalescent bacterial excretion is a key concern in managing Salmonella infections.
  • Factors influencing the duration of Salmonella shedding require further investigation.

Purpose of the Study:

  • To investigate factors affecting the length of convalescent Salmonella bacterial excretion in children.
  • To determine the prognostic influence of fever on Salmonella excretion duration.

Main Methods:

  • A cohort of 102 children diagnosed with Salmonella gastroenteritis was studied.
  • Data on fever severity and duration of bacterial excretion were collected and analyzed.
  • Statistical correlation was used to assess the relationship between fever and excretion length.

Main Results:

  • A significant correlation was observed between the degree of fever and the duration of bacterial excretion.
  • Children with higher fevers (≥40°C) exhibited the shortest excretion periods.
  • Children without fever showed the longest bacterial excretion durations.

Conclusions:

  • Fever appears to have a favorable prognostic influence on the duration of Salmonella excretion in children.
  • Monitoring fever may provide insights into the expected course of Salmonella shedding.
  • Further research could explore the mechanisms behind fever's effect on Salmonella excretion.

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