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Related Experiment Videos

The Allen-Fahey experiment extended.

Egbert de Boer1, Alfred L Nuttall, Ning Hu

  • 1Room D2-226, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. e.d.boer@hccnet.nl

The Journal of the Acoustical Society of America
|April 6, 2005
PubMed
Summary
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This study found that measuring cochlear amplifier gain using otoacoustic emissions and basilar membrane responses is not feasible. Wave interference likely explains why the cochlear amplifier

Area of Science:

  • Auditory Neuroscience
  • Bioacoustics
  • Otoacoustic Emissions

Background:

  • The cochlear amplifier is crucial for hearing sensitivity and frequency selectivity.
  • Previous attempts to measure its gain using otoacoustic emissions and auditory nerve responses yielded negative results.
  • Understanding the cochlear amplifier's gain is vital for diagnosing hearing loss.

Purpose of the Study:

  • To investigate an alternative method for measuring cochlear amplifier gain.
  • To compare distortion product otoacoustic emissions (DPOAEs) with basilar membrane mechanical responses.
  • To determine if the cochlear amplifier gain can be accurately estimated using these measurements.

Main Methods:

  • Experimental comparison of distortion product (DP) responses in the outer ear canal (otoacoustic emissions) with mechanical responses of the basilar membrane.

Related Experiment Videos

  • Utilizing a variation of Allen and Fahey's experiment, avoiding limitations in frequency ratios.
  • Analyzing DP generation and propagation mechanisms within the cochlea.

    • Main Results:

    • Results confirmed and extended previous findings that cochlear amplifier gain could not be measured using this approach.
    • No evidence supporting the measurement of cochlear amplifier gain via DPOAEs and basilar membrane responses was found.
    • A theoretical explanation involving wave interference affecting retrograde waves was proposed.

    Conclusions:

    • The gain of the cochlear amplifier cannot be reliably measured by comparing otoacoustic emissions with basilar membrane mechanical responses.
    • Wave interference, particularly between the two primary frequencies, likely attenuates the retrograde wave, impacting measurements.
    • Further research is needed to explore alternative methods for quantifying cochlear amplifier function.