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Updated: Aug 18, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
[CT differentiation of renal angiomyolipoma and renal cell carcinoma]
Jie Zhu1, Rong-bo Liu, Xiang-ping Zhou
1Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China.
Objective:
To improve the diagnosis of atypical renal angiomyolipoma (RAML) by use of CT to differentiate RAML from renal cell carcinoma (RCC).
Methods:
We retrospectively analyzed the CT manifestations with dual-phase enhanced contrast study in 36 cases of RAML (with 57 lesions) and 46 cases of RCC. 25 lesions of RAML and all RCC were histologically confirmed. Maximum likehood estimator was employed to discriminate all the lesions according to a series of indexes with statistical meanings.
Results:
Nine indexes were found to be significant and evident for separating RAML from RCC, namely "single or multiple", border, lobulation, protrusion rate, interface with cortex, angle with cortex, "levering-cortex-up" sign, characters of blood vessel in lesion and calcification. The accuracy rates of discrimination analysis for RAML and RCC were 93.0% and 89.1%, separately.
Conclusion:
The importance of 4 indexes, including protrusion rate, angle with cortex, "levering-cortex-up" sign and the traits of blood vessel, should be highlighted in the differentiation of RAML and RCC.

