Related Experiment Video
Updated: Jul 23, 2026
Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation
Published on: July 15, 2015
Use of perfusion parameters in predicting outcomes of machine-preserved kidneys
M F Mozes1, R B Skolek, B C Korf
1Gift of Hope Organ and Tissue Donor Network, Elmhurst, Illinois 60126, USA. mmozes@giftofhope.org
Abstract:
Perfusion parameters (PP) and early transplant outcome data from 332 consecutive ECD type kidneys machine preserved on the Waters RM-3 apparatus were reviewed and analyzed to examine the validity of using suboptimal PPs (renal resistance of .41-.60) as a criterion for discarding kidneys. Overall discard rate was 23.5%, with 55% of these having "poor" PP as part of reason for discard. PP analysis after 4 hours on the RM-3 is presented. This encompasses 280 kidneys with renal resistance .40. The PP-related discard rate in the renal resistance .41 to .60 kidneys was 51% versus 17% in the renal resistance
