Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

External-beam partial-breast irradiation.

Silvia C Formenti¹

¹Departmetn of Radiation Oncology, New York University School of Medicine, New York, NY, USA. silvia.formenti@med.nyu.edu

Seminars in Radiation Oncology

|April 6, 2005

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Determining Optimal Fractionation of Neoadjuvant Radiation in Low-Risk, Early-Stage Breast Cancer-Randomized SIGNAL Clinical Trial.

Cancers·2026

Same author

Radiation Oncology-Biology Integration Network: Bridging the Gap between Biological Research and Clinical Practice.

Clinical cancer research : an official journal of the American Association for Cancer Research·2026

Same author

Rewriting the radiation playbook: NSABP B-51 and the rise of pathologic precision.

NPJ breast cancer·2025

Same author

Facts and Hopes in Radioimmunotherapy for Localized Stages of Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research·2025

Same author

Author Correction: IL-17A-secreting γδ T cells promote resistance to CDK4/CDK6 inhibitors in HR<sup>+</sup>HER2<sup>-</sup> breast cancer via CX3CR1<sup>+</sup> macrophages.

Nature cancer·2025

Same author

IL-17A-secreting γδ T cells promote resistance to CDK4/CDK6 inhibitors in HR<sup>+</sup>HER2<sup>-</sup> breast cancer via CX3CR1<sup>+</sup> macrophages.

Nature cancer·2025

External-beam partial-breast radiation offers advantages over brachytherapy. This review examines its feasibility and challenges in cooperative oncology settings.

Area of Science:

Oncology
Radiation Oncology

Background:

Partial-breast irradiation (PBI) is often delivered via brachytherapy.
External-beam techniques for PBI present potential advantages but have limited published data.

Purpose of the Study:

To review the rationale and existing studies of external-beam partial-breast radiation.
To identify challenges and remaining issues with this radiation approach.

Main Methods:

Review of published randomized trials and pilot studies.
Focus on techniques including prone and supine positioning.
Analysis of a multi-institutional pilot trial in a cooperative oncology group setting.

Main Results:

Limited published experience exists for external-beam PBI.

Related Experiment Videos

Pilot studies from various institutions show varied approaches (e.g., prone, supine positioning).

A multi-institutional trial demonstrated rapid accrual, indicating significant interest.

Conclusions:

External-beam partial-breast radiation is of significant interest in oncology.
Further investigation is needed to address specific issues and challenges.
Feasibility in cooperative oncology settings is being explored.