Related Experiment Video
Updated: Aug 18, 2026

Using Multi-fluorinated Bile Acids and In Vivo Magnetic Resonance Imaging to Measure Bile Acid Transport
Published on: November 27, 2016
[FT-IR study on the solid-state reaction of bilirubin on BaF2]
1College of Chemistry and Molecular Engineering, Peking University, 100871 Beijing.
Abstract:
Bilirubinate complexes are the main component of pigment gallstones and the recent researches suggested that bilirubin free radical plays a role in some biological processes. In this paper the solid-state reaction of bilirubin on BaF2 was examined by FT-IR. The solid-state reaction was produced by grinding the crystalline bilirubin and single crystals BaF2 together in an agate mortar. From the results the free radical mechanism is suggested in the solid-state reaction of bilirubin on BaF2. The replacement of H on NH of pyrrole by Ba2+ was prior to that of H on COOH. The structure of the resultant complex from the solid-state reaction is different compared with that from the liquid-state reaction.
Related Concept Videos
Radical Substitution: Hydrogenolysis of Alkyl Halides with Tributyltin Hydride
The bonds formed in this reaction are stronger than the bonds broken, making it energetically favorable. The reaction follows a radical chain mechanism similar to radical halogenation reactions,...
Regioselectivity and Stereochemistry of Hydroboration
Hydroboration proceeds in a concerted fashion with the attack of borane on the π bond, giving a cyclic four-centered transition state. The –BH2 group is bonded to the less substituted carbon and –H to the more substituted carbon. The concerted nature requires the simultaneous addition of –H and –BH2 across the same face of the alkene giving syn stereochemistry.
Structure of Benzene: Kekulé Model
He proposed that benzene has a cyclic structure of six carbon atoms attached to one hydrogen atom each, with three alternating pi bonds.
Electrophilic Aromatic Substitution: Fluorination and Iodination of Benzene
Reactions of Aldehydes and Ketones: Baeyer–Villiger Oxidation
The carbonyl center is activated by...
Hydroboration-Oxidation of Alkenes

