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Updated: Jul 1, 2026
06:51
Mouse Model of Pressure Ulcers After Spinal Cord Injury
Published on: March 9, 2019
Pressure ulcers: guideline development and economic modelling
Rosa Legood1, Elizabeth McInnes
1Research Officer, Health Economics Research Centre, University of Oxford, Oxford, UK.
Journal of Advanced Nursing
|April 7, 2005
Summary
High-specification foam mattresses are cost-effective for preventing pressure ulcers. Incorporating economic evidence into clinical guidelines ensures pragmatic recommendations for patient care.
Area of Science:
- Healthcare Economics
- Clinical Practice Guidelines
- Preventive Medicine
Background:
- Previous UK guidelines for pressure-relieving devices lacked cost-effectiveness analysis.
- Integrating economic evidence into guidelines is a recent policy shift with limited research.
Purpose of the Study:
- To develop clinical guidelines for pressure-relieving devices, emphasizing economic evidence.
- To assess the clinical and cost-effectiveness of pressure-relieving devices for pressure ulcer prevention.
Main Methods:
- Systematic literature review of clinical and cost-effectiveness data.
- Economic modeling to evaluate comparative cost-effectiveness of devices.
- Guideline development group review including clinicians and patient representatives.
Main Results:
- High-specification foam mattresses significantly reduced pressure ulcer risk compared to standard mattresses.
- Economic modeling demonstrated high-specification foam mattresses are cost-effective due to reduced treatment costs.
- Evidence quality for other pressure-relieving devices was found to be weak.
Conclusions:
- Cost-effectiveness assessment is crucial for developing pragmatic clinical guidelines.
- Economic evaluation clarified evidence limitations and guided recommendations for pressure ulcer prevention.
- High-specification foam mattresses are recommended as minimum provision for at-risk patients.
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