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Genome Editing and Directed Differentiation of hPSCs for Interrogating Lineage Determinants in Human Pancreatic Development
Published on: March 5, 2017
Mending human genes: a job for a lifetime
1Auerback Melanoma Laboratory, UCSF Cancer Center, Box 0808, Room N431, University of California, San Francisco, CA 94143-0808, USA. jcleaver@cc.ucsf.edu
Abstract:
I have described a number of milestones along a career of nearly 40 years in DNA repair. Most important was the discovery that the human disease xeroderma pigmentosum represented mutations in various components of nucleotide excision repair. This ushered in a new field of research involving numerous investigators and which continues to expand and amaze.
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