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[Typical angina pectoris complaints without coronary macroangiopathy]
S Grönke1, M Schmidt, R H Schwinger
1Klinik III für Innere Medizin, Labor für Herzmuskelphysiologie und Molekulare Kardiologie, Universität zu Köln.
Deutsche Medizinische Wochenschrift (1946)
|April 7, 2005
Summary
Cardiac Syndrome X, characterized by chest pain without coronary artery disease, requires further investigation. Treatment focuses on improving endothelial function and quality of life for patients.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Cardiac Syndrome X presents as angina pectoris with normal coronary angiograms.
- Diagnosis is often challenging due to the absence of obstructive coronary artery disease.
Observation:
- A patient with exercise-induced chest pain and negative coronary angiography was evaluated.
- Adenosine testing revealed reduced coronary blood flow reserve.
- Myocardial scintigraphy (SPECT) showed inferior wall perfusion defects.
Findings:
- The patient was diagnosed with endothelial dysfunction, a hallmark of Cardiac Syndrome X.
- Coronary angiography excluded significant coronary artery stenosis.
Implications:
- Consider Cardiac Syndrome X in patients with exertional chest pain and normal coronary arteries.
- Invasive and non-invasive tests are crucial for diagnosis.
- Therapeutic strategies should target endothelial function improvement and symptom management to enhance quality of life.
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