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[Diagnostic image (232). A neonate with bilious vomiting].

A de Vries1, R R van Rijn

  • 1Afd. Kinderchirurgisch Centrum Amsterdam, Academisch Medisch Centrum/Universiteit van Amsterdam, locatie Emma Kinderziekenhuis, Postbus 22.700, 1100 DE Amsterdam. annebeth.devries@amc.uva.nl

Nederlands Tijdschrift Voor Geneeskunde
|April 9, 2005
PubMed
Summary

A premature infant developed ileal perforation and free gas, indicated by a football sign on X-ray. This serious complication was linked to indomethacin treatment.

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Area of Science:

  • Neonatal Medicine
  • Pediatric Surgery
  • Gastroenterology

Background:

  • Premature infants often require medical interventions for various health issues.
  • Indomethacin is a nonsteroidal anti-inflammatory drug commonly used to manage patent ductus arteriosus and other conditions in neonates.

Observation:

  • A premature infant presented with acute abdominal distension and bilious vomiting.
  • Radiographic examination revealed a 'football sign,' indicative of pneumoperitoneum (free air in the abdominal cavity).

Findings:

  • The infant's condition was attributed to infarction and subsequent perforation of the ileum.
  • This gastrointestinal complication was identified as a consequence of indomethacin administration.

Implications:

Related Experiment Videos

  • This case highlights a rare but severe adverse effect of indomethacin in premature neonates.
  • Early recognition and surgical intervention are crucial for managing indomethacin-induced bowel perforation.
  • Awareness of this complication is essential for neonatologists and pediatric surgeons when prescribing indomethacin.