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Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
Published on: June 28, 2021
[The epidemiological considerations in acute pancreatitis. A comparison between 2 series]
P Alvarez Blanco1, A Ruiz de Aguiar González, R Bañares Cañizares
1Servicio de Medicina Interna IV, Hospital Universitario San Carlos, Madrid.
Abstract:
Epidemiological data from two series of patients in whom acute pancreatitis (AP) was diagnosed, with a chronological difference of four years between them, were compared. A total of 142 events of AP were analyzed from 128 clinical records. The mean age of incidence was significantly higher among the most recent series (61.04 +/- 17.83 years vs 51.66 +/- 14.06 years), and no differences were observed with regard to distribution by sex. The most frequent etiology in both series was biliary lithiasis, followed by ethylism, both of them clearly associated with female and male sex, respectively. In the AP of alcoholic etiology, the mean age at onset was smaller than in the other etiological groups and this observation was more evident in the second series. Finally, mortality was significantly reduced in the most recent series (12.3% for the first series vs 5.7% for the second series).
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Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
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