[Thrombolytic treatment in stroke in patients with intracardiac thrombus: presentation of one case]
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Updated: Aug 18, 2026

Prehospital Thrombolysis: A Manual from Berlin
Published on: November 26, 2013
T Segura1, M Herrera, S Garcia-Muñozguren
1Sección de Neurología, Hospital General Universitario de Albacete, Hermanos Falcó, s/n, 02006 Albacete, Spain. tseguram@meditex.es
Intravenous tissue plasminogen activator (t-PA) is a recent proven effective treatment for acute ischemic stroke patients. However, the use of t-PA in some special settings is controversial. One of these is the presence of a cardiac thrombus, given that the use of t-PA could potentially accelerate breakup of the thrombus and cause additional embolisms. The authors describe the case of a cardiological patient with a cardiac thrombus who was given IV t-PA for acute stroke treatment without complications. We discuss the necessity or not of a 24 hours delay before anticoagulants administration in these special patients.
Intravenous tissue plasminogen activator (t-PA) is a recent proven effective treatment for acute ischemic stroke patients. However, the use of t-PA in some special settings is controversial. One of these is the presence of a cardiac thrombus, given that the use of t-PA could potentially accelerate breakup of the thrombus and cause additional embolisms. The authors describe the case of a cardiological patient with a cardiac thrombus who was given IV t-PA for acute stroke treatment without complications. We discuss the necessity or not of a 24 hours delay before anticoagulants administration in these special patients.
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