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Influenza and its relationship to circulatory disorders
D M Fleming1, K W Cross, R S Pannell
1Birmingham Research Unit of the Royal College of General Practitioners, Harborne, Birmingham, UK. dfleming@rcgpbhamresunit.nhs.uk
Epidemiology and Infection
|April 9, 2005
Summary
Influenza epidemics significantly increase circulatory deaths, especially in older adults, with no rise in hospital admissions. This suggests rapid mortality during acute respiratory illness, impacting public health planning.
Area of Science:
- Epidemiology
- Public Health
- Cardiology
Background:
- Influenza is a significant public health concern.
- The impact of influenza on circulatory disease mortality requires further investigation.
Purpose of the Study:
- To investigate the impact of influenza epidemics on circulatory disease mortality.
- To analyze the relationship between influenza, respiratory episodes, and circulatory deaths.
Main Methods:
- Utilized general practice episode data, hospital admission data, and mortality data from 1994-2000.
- Analyzed weekly data during influenza epidemic periods for age groups 45-75+.
- Calculated cross-correlation coefficients to examine associations between variables at different time lags.
Main Results:
- Increased circulatory deaths observed across all age groups during influenza epidemics, particularly in those aged 75 and older.
- No concurrent increase in general practice episodes or emergency hospital admissions for circulatory disorders.
- High correlation between respiratory episodes and circulatory/respiratory deaths, indicating contemporaneous events.
Conclusions:
- Influenza epidemics are associated with a substantial increase in circulatory deaths, often occurring rapidly during acute illness.
- Findings suggest a need to consider circulatory mortality in influenza contingency planning and resource allocation.
- Public health strategies should address the heightened risk of cardiovascular events during influenza seasons.
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