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Updated: Aug 18, 2026
Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb
Published on: January 17, 2025
Diagnosis and surgical treatment of primary hepatic cholangiocarcinoma
Shao-liang Han1, Guan-bao Zhu, Jian-gao Yao
1Department of General Surgery, the First Affiliated Hospital of Wenzhou Medical College, Wenzhou, Zhejiang Province, PR China. slhan88@hotmail.com
Background/Aims:
To summarize the experience in the diagnosis and surgical treatment of primary hepatic cholangiocarcinoma (PHCC).
Methodology:
Forty-seven PHCC patients, who had undergone surgical treatment in our hospital from 1970 to 1999, were retrospectively analyzed with their clinicopathological features, surgical treatments and prognoses.
Results:
1) PHCC patients lacked typical clinical manifestation, and some had an accompanying history of virus B hepatitis (36.2%, 17/47) and liver cirrhosis (46.8%, 23/47), and elevation of AFP (25.5%, 12/47). 2) The detection rates of BUS, CT, MRI and liver scintigraphy were 95.7% (45/47), 93.6% (44/47), 100% (23/23) and 100% (4/4), respectively. The lesions detected by those methods needed to differentiate with hepatocellular carcinoma. 3) The resection rate was 76.6% (36/47), the postoperative overall 1-, 3- and 5-year survival rates were 54.1% (24/47), 34.0% (16/47), and 29.8% (14/47) in all patients, respectively, including the 1-, 3- and 5-year survival rates were 83.3% (30/36), 50.0% (18/36), and 38.9% (14/36) in hepatectomy cases, respectively. 4) All of the four patients who survived more than 5 years, including small liver cancer (< or = 3 cm) three cases and encapsulated large nodular lesion one case, received curable resection and postoperative adjuvant therapies.
Conclusions:
PHCC patients can obtain a better result by early detection and curative resection with adjuvant therapies.
