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Related Experiment Videos

The empty sella syndrome: much ado about nothing.

G D Braatvedt1, R J Corrall

  • 1Bristol Royal Infirmary.

British Journal of Hospital Medicine
|April 1, 1992
PubMed
Summary

Empty sella syndrome is the most frequent cause of an enlarged pituitary fossa found incidentally on imaging. This condition involves the pituitary fossa filling with cerebrospinal fluid and is typically benign, but requires differentiation from pituitary tumors.

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Area of Science:

  • Radiology
  • Endocrinology
  • Neuroanatomy

Background:

  • Empty sella syndrome is the most common incidental finding of an enlarged pituitary fossa.
  • It is characterized by the pituitary fossa being partially or wholly filled with cerebrospinal fluid.

Purpose of the Study:

  • To highlight the significance of empty sella syndrome as a differential diagnosis for enlarged pituitary fossa.
  • To emphasize the importance of distinguishing this benign condition from sellar expansion caused by pituitary tumors.

Main Methods:

  • Review of radiological findings associated with empty sella syndrome.
  • Anatomical description of the pituitary fossa and its contents.

Main Results:

  • Empty sella syndrome is the leading cause of radiologically enlarged pituitary fossae.
  • The condition is anatomically defined by cerebrospinal fluid within the fossa.

Conclusions:

  • Empty sella syndrome is generally an innocuous finding.
  • Distinguishing empty sella syndrome from pituitary tumors is crucial in clinical practice.

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