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Neonatal suppurative submandibular sialadenitis.

Lisa Weibel¹, Philippe Goetschel, Roland Meier

¹Department of Pediatrics, University Children's Hospital of Zurich, 8032 Zurich, Switzerland.

The Pediatric Infectious Disease Journal

|April 9, 2005

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Neonatal sialadenitis, an infection of the salivary glands, can affect newborns. Staphylococcus aureus was the cause in most reported cases, particularly in premature infants receiving gavage feeding.

Area of Science:

Neonatal Medicine
Pediatric Infectious Diseases
Otolaryngology

Background:

Neonatal sialadenitis is a rare condition affecting salivary glands in newborns.
Submandibular gland involvement is the most common presentation.
Staphylococcus aureus is frequently implicated as the causative agent.

Purpose of the Study:

To describe two cases of full-term newborns with submandibular gland sialadenitis caused by Staphylococcus aureus.
To review the English language literature on isolated submandibular sialadenitis in neonates.

Main Methods:

Case report of two neonates.
Literature review of previously reported cases.

Main Results:

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Two full-term newborns presented with submandibular sialadenitis without identifiable risk factors.

Literature search identified 15 previous cases of isolated submandibular sialadenitis.

Staphylococcus aureus was the pathogen in 87% of all reported cases.

The condition predominantly affected premature, gavage-fed neonates (87%).

Conclusions:

Neonatal submandibular sialadenitis, though rare, can occur in full-term infants.
Staphylococcus aureus is the primary pathogen, with a strong association with prematurity and gavage feeding in the majority of cases.