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Updated: Aug 7, 2026
07:27
Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Catheter-based interventional palliation for hypoplastic left heart syndrome
Mark M Boucek1, Cristine Mashburn, Kak-Chen Chan
1Division of Pediatric Cardiology, The Department of Pediatrics, University of Colorado Health Sciences Center, Denver, USA.
Summary
Catheter-based interventions stabilize infants with hypoplastic left heart syndrome (HLHS) awaiting heart transplants. Ductal stenting and pulmonary artery banding offer effective palliation, improving long-term survival rates.
Area of Science:
- Pediatric Cardiology
- Interventional Cardiology
- Congenital Heart Disease
Background:
- Hypoplastic left heart syndrome (HLHS) requires complex management, often involving stabilization before heart transplantation.
- Key palliative goals include maintaining ductal patency, decompressing the left heart, and regulating pulmonary blood flow.
Purpose of the Study:
- To review the experience and outcomes of catheter-based interventional palliation in infants with HLHS.
- To evaluate the effectiveness and safety of ductal stenting and internal pulmonary artery banding.
Main Methods:
- Retrospective review of 40 infants with HLHS undergoing ductal stenting.
- Analysis of 17 of these infants who also received internal pulmonary artery bands.
- Assessment of procedural outcomes, duration of palliation, and long-term survival.
Main Results:
- One procedure-related death occurred after balloon septostomy.
- Late survival was 75% for infants receiving long-term palliation or transplantation.
- Internal pulmonary artery bands effectively protected the pulmonary artery bed without requiring reconstruction or causing late stenoses.
- Mesoversion was associated with increased procedural and late complications.
Conclusions:
- Catheter-based interventional palliation is a proven strategy for stabilizing infants with HLHS.
- Continued advancements in experience and technology may expand the applicability of these interventions for HLHS patients.
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