Related Experiment Video
Updated: Aug 18, 2026

Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
[Aeromonas caviae infection mimicking inflammatory bowel disease in a child]
E J van der Gaag1, E Roelofsen, R F H M Tummers
1Universitair Medisch Centrum Groningen, locatie Beatrix Kinderkliniek, Postbus 30.001, 9700 RB Groningen. e.j.van.der.gaag@bkk.umcg.nl
Insights
Aeromonas caviae can cause severe pancolitis in children, presenting as bloody diarrhea. This rare case resolved spontaneously, with no signs of inflammatory bowel disease after 24 months.
Area of Science:
- Microbiology
- Pediatrics
- Gastroenterology
Background:
- Inflammatory bowel disease (IBD) has a significant genetic component and can manifest in childhood.
- Infectious gastroenteritis is common in children, but severe presentations like pancolitis are less frequent.
Observation:
- A 10-year-old girl presented with severe pancolitis and bloody diarrhea.
- Stool cultures revealed a monoculture of Aeromonas caviae.
- The patient had a family history suggestive of IBD.
Findings:
- The patient's condition resolved spontaneously without specific treatment.
- No signs of IBD were observed during a 24-month follow-up.
- This case represents a severe manifestation of Aeromonas caviae infection, distinct from typical mild diarrhea and rare among 188 Aeromonas-positive cases in a 5-year hospital database.
Implications:
- Aeromonas caviae should be considered in the differential diagnosis of pediatric pancolitis, even with a family history of IBD.
- Spontaneous resolution is possible, suggesting host factors may influence disease severity.
- Further research is needed to understand the pathogenesis of severe Aeromonas infections in children.
Abstract:
A 10-year-old girl presented with a pancolitis with watery bloody diarrhoea. Her family history revealed the presence of inflammatory bowel disease. Whilst awaiting the diagnostic tests results, the stool cultures showed Aeromonas caviae. The disease resolved spontaneously. After 24 months there were no further signs of illness, notably no inflammatory bowel disease. This case represents a more severe form than the mild diarrhoea that is usually described in the literature. In a retrospective search of the hospital database, covering the previous 5 years, 188 patients with positive Aeromonas cultures were found, but the patient described was the only one with bloody diarrhoea with a monoculture positive for A. caviae.
Related Concept Videos
Amebiasis
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease III: Crohn's Disease
Inflammatory Bowel Disease IV: Clinical Manifestations
Atypical Pneumonia
Inflammatory Bowel Disease I: Introduction
