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Global real-time quantification/reverse transcription-polymerase chain reaction for detecting proto-oncogenes
Haematologica
|April 12, 2005
Abstract:
A global real-time quantitative/reverse transcription-polymerase chain reaction technique for detecting the expression of six 14q32 chromosomal translocation-associated proto-oncogenes in marrow plasma cells was established and applied to myeloma specimens. This technique is an alternative method of detecting 14q32 rearrangements and allows investigation of the relationship between proto-oncogene expression and clinical features.

