Related Experiment Video
Updated: Aug 9, 2026
08:50
5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
Published on: July 3, 2013
Renal outcome following heminephrectomy for duplex kidney
M S Gundeti1, P G Ransley, P G Duffy
1Department of Paediatric Urology, Great Ormond Street Hospital for Children's NHS Trust and Evelina Children's Hospital, Guy's Hospital, London, United Kingdom.
The Journal of Urology
|April 12, 2005
Summary
Heminephrectomy in duplex kidneys resulted in a significant function decrease in 8% of patients. Over half experienced a small decrease in the remaining kidney
Area of Science:
- Urology
- Pediatric Surgery
- Nephrology
Background:
- Duplex kidneys are a common congenital anomaly.
- Heminephrectomy is a surgical procedure to remove half of a kidney.
- Evaluating functional outcomes post-heminephrectomy is crucial for patient management.
Purpose of the Study:
- To assess the functional outcomes after heminephrectomy in patients with duplex kidneys.
- To analyze the impact of heminephrectomy on the remaining renal moiety function.
Main Methods:
- Retrospective review of 60 patients who underwent heminephrectomy for duplex kidneys (1995-2000).
- Analysis of patient demographics, diagnosis, and kidney characteristics (unilateral/bilateral duplex, ureterocele).
- Nuclear renography used to measure kidney function before and after surgery.
Main Results:
- Mean renal function of the duplex kidney decreased from 39.9% to 33.1% post-heminephrectomy.
- A significant decrease (>10%) in function was observed in 5 patients (8%).
- 51% of patients experienced a small decrease (<10%) in the remaining moiety's function.
Conclusions:
- Heminephrectomy in duplex kidneys can lead to a significant functional decrease in a small percentage of patients.
- A notable proportion of patients experience a minor reduction in the remaining kidney's function post-surgery.
- These findings highlight the importance of careful functional assessment after heminephrectomy.
More Related Videos
Related Concept Videos
01:28Kidney Transplant I: Introduction
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
01:26Kidney Transplant II: Surgical Procedure
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
01:16Kidney Transplant III: Nursing Management
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
01:29Acute Kidney Injury II: Pathophysiology
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
01:29Acute Kidney Injury III: Clinical Manifestations
Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...