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Updated: Aug 18, 2026

Assessment of Vascular Tone Responsiveness using Isolated Mesenteric Arteries with a Focus on Modulation by Perivascular Adipose Tissues
Published on: June 3, 2019
[Structural and functional characteristics of cardiovascular system in elderly patients with borderline hypertension]
Insights
Elderly individuals with borderline hypertension exhibit significant heart and vessel remodeling, similar to those with higher blood pressure. This condition increases cardiovascular complication risk due to age and hypertension factors.
Area of Science:
- Cardiology
- Gerontology
- Vascular Medicine
Background:
- Aging and hypertension significantly impact cardiovascular health.
- Borderline hypertension in the elderly is not well-characterized regarding cardiac and vascular remodeling.
- Understanding these changes is crucial for predicting cardiovascular risk.
Purpose of the Study:
- To investigate the structural and functional state of the heart and vessels in elderly patients with borderline hypertension.
- To compare cardiac and vascular remodeling in borderline hypertensive elderly patients with those having normal or higher blood pressure.
- To assess the cardiovascular complication risk associated with borderline hypertension in the elderly.
Main Methods:
- Comparative analysis of cardiac and vascular structure and function.
- Echocardiography and vascular stiffness measurements were likely employed (inferred).
- Inclusion of elderly patients with normal, borderline, and higher blood pressure levels for comparison.
Main Results:
- Elderly patients with borderline hypertension showed significant heart and vessel remodeling.
- Hypertension and age were substantial contributors to remodeling.
- Borderline hypertensive patients exhibited greater myocardial mass, left ventricular hypertrophy, and diastolic dysfunction compared to normotensive controls.
- Vascular stiffness was higher than age-specific norms in those with borderline hypertension.
Conclusions:
- Borderline hypertension in the elderly is associated with cardiac and vascular remodeling patterns similar to established hypertension.
- These remodeling changes indicate an elevated risk for cardiovascular complications in this demographic.
- Early identification and management of borderline hypertension in the elderly are warranted.
Abstract:
Structural and functional state of the heart and vessels was studied in elderly patients with borderline hypertension. Remodeling in these patients was compared with that in patients of the same age with normal or higher blood pressure levels. Analysis revealed substantial contribution in remodeling of both age and hypertensive factors. Compared with subjects with normal blood pressure patients with hypertension had greater myocardial mass, higher frequency of left ventricular hypertrophy with cases of concentric hypertrophy and isolated hypertrophy of interventricular septum. Elderly patients with borderline hypertension had more pronounced disturbances of diastolic function. Overall characteristics of patients with borderline hypertension were similar to those found in the elderly with higher level of hypertension. Presence of borderline hypertension was associated with higher than age specific stiffness of vessels. Character and degree of remodeling of the heart and vessels in the elderly patients with borderline hypertension evidence for elevated risk of cardiovascular complications.
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