Related Experiment Video
Updated: Aug 18, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Acquired ileal atresia in infancy: report of two cases
Simmi K Ratan1, K N Rattan, S K Mathur
1Department of Paediatric Surgery, Pt BD Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India. drjohnsimmi@yahoo.com
Insights
Acquired ileal atresia in infants can rapidly develop after diarrhea, potentially due to strangulation or thromboembolic events. Early surgical detection is crucial for these rare intestinal obstruction cases.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Neonatal Medicine
Background:
- Acquired ileal atresia is a rare condition in infants, often presenting with intestinal obstruction.
- The etiology of acquired ileal atresia is not fully understood, with theories including strangulation and inflammation.
Observation:
- This report details two infants (3 and 4 months old) with acquired distal ileal atresia following a diarrheal episode.
- Both infants presented with symptoms of intestinal obstruction, with a short interval (2 weeks) between symptom onset and surgical diagnosis.
Findings:
- The rapid progression suggests strangulation with resorption of gangrenous bowel or a thromboembolic phenomenon as potential causes.
- One infant had intussusception noted on sonography; the other had a high-lying cecum and long mesentery, possibly predisposing to volvulus.
Implications:
- The findings highlight the importance of considering thromboembolic events in the etiology of acquired ileal atresia.
- Prompt diagnosis and surgical intervention are critical for managing this rare neonatal surgical emergency.
- Further research into the specific mechanisms underlying acquired ileal atresia is warranted.
Abstract:
Two infants, aged 3 months and 4 months, with acquired ileal atresia in the distal ileum are described. Both of them presented with features of intestinal obstruction following a diarrhoeal episode. In both patients the time interval between the onset of symptoms and detection of atresia at surgery was very short, i.e. 2 weeks. In our opinion, strangulation with subsequent resorption of gangrenous gut could have been the underlying mechanism in both patients. However, a short interval between initiation of symptomatology and detection of atresia prompted us to postulate a thromboembolic phenomenon as the cause of these lesions. While in one patient intussusception was noted on sonography, in the other there was no clear-cut aetiology present except for a high-lying caecum with a long mesentery that might have led to volvulus. We have reviewed the pertinent literature of this very rare sequela of gut inflammation.
Related Concept Videos
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Intestinal Obstruction II: Pathophysiology
Intestinal Obstruction I: Introduction