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Updated: Aug 18, 2026

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
Published on: March 20, 2015
[Surface-enhanced Raman spectroscopy of riboflavin in silver colloids using 1 064 nm excitation]
Abstract:
Surface-enhanced Raman spectra (SERS) of riboflavin in silver colloids, using near-infrared (NIR) laser operating at 1 064 nm wavelength, were obtained. The enhancement factor was further increased by improving the preparation of silver colloid and with the addition of a small amount of NaOH. The detection limit was lower than 3.2 x 10(-10) mol x L(-1). It is concluded that the larger and aggregated silver particles were more efficient for the electromagnetic enhancement of NIR-SERS. Flavin ring was absorbed on the colloidal silver methal surface, standing on oxygens of C(20)=O) and C(4)=O.
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