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Updated: Aug 18, 2026

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation
Published on: July 10, 2012
[Children bronchiolitis: multicentric study in Tunis]
Rafla Tej Dellagi1, Raoudha Tagorti, Basma Massoudi
1Service Régional des Soins de Santé de Base de Tunis.
Insights
This study found that bronchiolitis affects 10% of young children in Tunis during winter. Promiscuity was a significant risk factor, with many cases requiring hospitalization and specific treatments.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Child serious respiratory infections pose a significant public health challenge.
- Basic healthcare programs aim to combat these infections in young children.
Purpose of the Study:
- To determine the winter frequency of bronchiolitis in children aged 1-36 months.
- To analyze the severity, clinical profile, treatment patterns, and environmental risk factors of bronchiolitis.
- To evaluate the role of basic healthcare services in managing pediatric respiratory infections.
Main Methods:
- A multicentric, cross-sectional study conducted in Tunis from January to March 1999.
- Involved a sample size of 1340 pediatric patients.
- Data collected on disease frequency, patient demographics, clinical presentation, risk factors, and therapeutic interventions.
Main Results:
- Bronchiolitis occurred in 10% of patients, with a median age of 9 months.
- Aggravating factors were present in 73% of cases, and secondary infections in 70%.
- Social promiscuity was the only statistically significant environmental risk factor. Hospitalization was required for 14.2% of cases.
Conclusions:
- Basic healthcare structures are effective for winter management of pediatric respiratory infections.
- Continuous training for healthcare professionals and adequate technical staff are crucial for optimal outcomes.
- Bronchodilators, corticoids, and antibiotics were frequently prescribed, highlighting the need for evidence-based treatment guidelines.
Abstract:
This study is made in the general framework of the basic health cares program set up by Tunis regional service to fight child serious respiratory infections. It has an objective to measure bronchiolitis winter frequency for patients aged from 1 to 36 months, serious cases frequency, changing profile, the therapeutic behavior and environmental risk factors. This is a multicentric transversal study in grappa, it has taken place in Tunis between January and march 1999 with a sample size of 1340 patients. Result of the survey has shown a medium frequency of the disease with 10% of the patients, median age group infected at 9 months, aggravating factor in 73% of cases, and a surinfection in 70% of cases. Promiscuity is the only environmental risk factor which is statistically significant. Hospitalization was necessary in 14.2% of cases. With regard to prescriptions, bronchodilators, corticoids and antibiotics were prescribed for respectively 71, 39, and 45.6% of patients. Basic health cares structure is a good alternative during the winter season, provided human expertise's are constantly updated and adequate technical staff is available.