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[Acral acanthosis nigricans paraneoplastic: about one case]
Chadia Sidhom1, Dalenda El Euch, Sadok Hammami
1Centre Médico-Social des Communications, Tunis.
La Tunisie Medicale
|April 13, 2005
Summary
Paraneoplastic acanthosis nigricans, a skin condition, was linked to visceral neoplasms in a patient. Resolution of lung and bladder cancers led to the disappearance of this skin manifestation.
Area of Science:
- Dermatology
- Oncology
Background:
- Paraneoplastic acanthosis nigricans is a rare skin disorder associated with internal malignancies.
- Understanding its presentation and association with specific cancers is crucial for diagnosis.
Observation:
- A 63-year-old patient presented with acanthosis nigricans on the dorsal aspect of the right second, third, and fourth toes.
- Initial investigations revealed an associated right lung carcinoma.
Findings:
- Resection of the lung carcinoma resulted in near-complete resolution of the acanthosis nigricans.
- Recurrence of acanthosis nigricans five years later indicated a newly diagnosed bladder carcinoma.
Implications:
- This case highlights the potential for acanthosis nigricans to be a recurrent marker for distinct visceral neoplasms.
- Successful treatment of the underlying cancer led to the regression of the skin condition, emphasizing the importance of this association.