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Published on: February 23, 2014
[Review on the etiology and treatment of bacterial pneumonias]
Nina Hrabac1, Sarija Agić, Sead Jazić
1Opća bolnica Sarajevo, Bosna i Hercegovina.
Abstract:
The bacterial pneumoniae are the significant factor of morbidity and mortality all over the world. So USA are at the sixth place per mortality cause. The bacteria are in 60-80% of cases the causes of pneumonia in the communities. Therefore this is the review on the ethiology of the verification and treatment of pneumonias in the 17-month period in the General hospital "Sarajevo". In the period of the 1st January 2002 till the 31st May 2003 year, it was examined 105 sputa on the antibiogram, and in 12 cases (11.4%) was found the positive bacterial finding. Most often were gram negative bacteria in 7 cases (58.3%), while were found the gram positive in 5 patients (41.7%). Therefore that the majority of the examinees belonged to the risk group, and that were the patients with over 50 years of age 11 (78.6%), with the chronic obstructive lung disease 5 (35.7%), with the malignant disease 1 (7.1%) and with the coinfection of the urinary tract. E. coli was found in 3 patient (25.0%), Kl. Pneumoniae in 2 (16.7%), Ps. aeruginosis in 1 (8.3%), Citrobacter freundi in 1 (8.3%), and in 2 cases (16.7%) were isolated. Staphylococcus intermedius and Streptococcus beta haemolyticus gr. A and Str. Pneumoniae in 1 case (8.3%). To the patients with the positive finding of sputum on antibiogram were most often administered empirically cefalosporia of the third generation because it was about the more severe patients, then the combination of ampicillin with gentamicin. All were dismissed as recovered or in better condition. Pneumonias is in the risk groups are possible to prevent to the five-years pneumococcus vaccine when is indicated or by influenza vaccine when simultaneously was prevented the viral, that is the possible bacterially superinfected pneumonia.
Insights
Bacterial pneumonia is a major global health concern. This review identified common bacteria causing pneumonia in Sarajevo, highlighting effective empirical treatments and preventive strategies for at-risk populations.
Area of Science:
- Infectious Diseases
- Microbiology
- Public Health
Context:
- Bacterial pneumonias are a significant cause of global morbidity and mortality.
- Community-acquired bacterial pneumonia accounts for 60-80% of pneumonia cases.
- The United States ranks sixth globally in pneumonia-related mortality.
Purpose:
- To review the etiology, verification, and treatment of bacterial pneumonias.
- To analyze sputum antibiogram findings over a 17-month period.
- To identify common bacterial pathogens and assess treatment outcomes in a hospital setting.
Summary:
- A 17-month study (Jan 2002-May 2003) at General Hospital "Sarajevo" examined 105 sputum samples for antibiograms, revealing positive bacterial findings in 12 cases (11.4%).
- Gram-negative bacteria (58.3%) were more prevalent than Gram-positive bacteria (41.7%). Key isolates included E. coli, Kl. Pneumoniae, and Ps. aeruginosis.
- The majority of patients were in risk groups: over 50 years old (78.6%), with chronic obstructive lung disease (35.7%), or malignant disease (7.1%).
- Empirical treatment with third-generation cephalosporins or ampicillin/gentamicin combinations was effective, with all patients recovering or improving.
- Preventive measures include pneumococcus and influenza vaccines, crucial for reducing bacterial superinfections in at-risk individuals.
Impact:
- Provides insights into the microbiological landscape of community-acquired pneumonia in Sarajevo.
- Informs empirical treatment strategies for severe pneumonia cases.
- Emphasizes the importance of vaccination in preventing bacterial pneumonia and superinfections in vulnerable populations.
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