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Updated: Aug 18, 2026

Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
Published on: April 29, 2014
[The local recurrence of renal-cell carcinoma after nephron-sparing surgery]
Abstract:
The possibility of local recurrence in the remnant of kidney is the main limitation of nephron-sparing surgery in the patients with renal-cell carcinoma. The results of conservative surgery were analyzed in 176 patients. The local recurrences were revealed in 6.3% patients (5.1% in the imperative group and 1.2%--in elective group). Cancer multifocality was the source of recurrence in 8 patients, positive surgical border of the tumor--in 3. The type of surgical intervention (enucleation, enucleoresection, resection) doesn't affect the frequency of tumor local recurrence. The careful monitoring with the help of modern methods of visual diagnosis during the patient whole life is the main problem in the prophylaxis of such pathology.
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