Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

A case with multiple gynecological malignancies.

B O Goker¹, T Bese, S Ilvan

¹Department of Obstetrics and Gynecology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society

|April 13, 2005

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Role of molecular driver mutations in recurrence of early-stage laryngeal cancer following narrow field definitive radiotherapy.

Oral oncology reports·2026

Same author

Psychosocial outcome of COVID-19 patients requiring ventilation after ECMO versus long-term mechanical ventilation.

Frontiers in cardiovascular medicine·2026

Same author

Rucaparib maintenance for newly diagnosed advanced ovarian cancer: interim overall survival, progression-free survival, and safety at 5 years of follow-up from the phase III ATHENA-MONO/GOG-3020/ENGOT-ov45 study.

Annals of oncology : official journal of the European Society for Medical Oncology·2025

Same author

WEIGHT LOSS AND BEYOND, ASSESSMENT OF QUALITY OF LIFE AFTER LAPAROSCOPIC SLEEVE GASTRECTOMY USING BAROS IN PATIENTS WITH OBESITY IN TURKEY.

Acta endocrinologica (Bucharest, Romania : 2005)·2024

Same author

Predictive value of the frontal QRS-T angle for a permanent pacemaker requirement in patients undergoing transcatheter aortic valve implantation.

European review for medical and pharmacological sciences·2023

Same author

The effect of L-thyroxine treatment on ventricular dysfunction and pulmonary arterial stiffness in patients with subclinical hypothyroidism.

European review for medical and pharmacological sciences·2022

This case study details a patient who developed multiple cancers, including non-Hodgkin lymphoma, endometrial adenocarcinoma, and vaginal cancers. Investigations revealed immune system factors like CD4+ lymphopenia and Epstein-Barr virus infection potentially contributing to the malignancies.

Area of Science:

Oncology
Immunology
Pathology

Background:

A patient diagnosed with cervical non-Hodgkin lymphoma received chemotherapy.
Subsequent development of secondary and tertiary malignancies, including endometrial adenocarcinoma and vaginal squamous cell carcinoma, occurred over time.

Observation:

The patient presented with a complex medical history involving multiple primary cancers.
Diagnostic investigations identified CD4+ lymphopenia, positive Epstein-Barr virus serology, and low-risk human papillomavirus detection.

Findings:

The patient developed a sequence of malignancies: non-Hodgkin lymphoma, endometrial adenocarcinoma, vaginal squamous cell carcinoma, and postradiational vaginal sarcoma.
Immune system analysis revealed CD4+ lymphopenia and Epstein-Barr virus infection, while human papillomavirus was detected in cervical smears.

Related Experiment Videos

Implications:

This case highlights the potential for multiple primary malignancies in a single patient.
Investigating immune status and viral associations may be crucial in understanding complex cancer development and progression.