Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The cross-sectional cohort study: an underutilized design.

James I Hudson1, Harrison G Pope, Robert J Glynn

  • 1Biological Psychiatry Laboratory, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA. jhudson@mclean.harvard.edu

Epidemiology (Cambridge, Mass.)
|April 13, 2005
PubMed
Summary

Epidemiologists can use a novel cross-sectional cohort study design to assess exposure-outcome associations. This method is advantageous for chronic conditions with long latency periods, like psychiatric disorders.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Enlightenment in a Pill-Testing the Efficacy of Psilocybin.

JAMA psychiatry·2026
Same author

Comment on Buse et al. Prevalence of Hypercortisolism in Difficult-to-Control Type 2 Diabetes. Diabetes Care 2025;48:2012-2020.

Diabetes care·2026
Same author

The Role of Impulsivity in Anabolic-Androgenic Steroid Use.

Performance enhancement & health·2025
Same author

Genome-wide association studies of binge eating behaviour and anorexia nervosa yield insights into the unique and shared biology of eating disorder phenotypes.

medRxiv : the preprint server for health sciences·2025
Same author

American Psychiatrists' Opinions About Classic Hallucinogens and Their Potential Therapeutic Applications: A 7-Year Follow-Up Survey.

Psychedelic medicine (New Rochelle, N.Y.)·2025
Same author

A study of long-term supraphysiologic-dose anabolic-androgenic steroid use on cognitive function in middle-aged men.

The American journal of drug and alcohol abuse·2024

Area of Science:

  • Epidemiology
  • Biostatistics

Background:

  • Traditional epidemiological study designs include case-control, prospective cohort, and retrospective cohort studies.
  • These designs are used to estimate associations between exposures and outcomes in a population over time.

Purpose of the Study:

  • To introduce and describe the "cross-sectional cohort study" design as an alternative epidemiological method.
  • To highlight the potential advantages and limitations of this design.

Main Methods:

  • The cross-sectional cohort study design involves sampling a source population at a single point in time (cross-sectionally).
  • Investigators then retrospectively assess subjects' histories of exposures and outcomes over a defined period.

Main Results:

Related Experiment Videos

  • This design may offer advantages over traditional methods, particularly for chronic or episodic conditions with low mortality.
  • Situations favoring this design include long intervals between exposure and outcome, accurate retrospective assessment capabilities, and outcomes that do not accelerate population exiting.

    • Conclusions:

    • The cross-sectional cohort study design is a valuable alternative for specific epidemiological research scenarios.
    • Careful consideration of validity threats, such as nonignorable exiting and retrospective measurement error, is crucial for its effective implementation.