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Occupation and risk of pancreatic cancer: a population-based case-control study in iowa
Yawei Zhang1, Kenneth P Cantor, Charles F Lynch
1Yale University School of Public Health, New Haven, Connecticut 06520, USA. tongzhang.zheng@yale.edu
Objective:
Previous epidemiological studies have inconsistently linked various occupations and industries to pancreatic cancer risk.
Methods:
We analyzed data from a population-based case-control study conducted in Iowa involving 376 histologically confirmed incident pancreatic cancer cases and 2434 control subjects.
Results:
A significantly increased risk was observed among men who worked in the following industries: chemical and allied products, transportation, and elementary and secondary schools. Increased risks also were observed in men who were employed as truck drivers; railroad brake, signal, and switch operators; purchasing agents and buyers; teachers; insurance agents; and retail supervisors. Among women, a significantly increased risk of pancreatic cancer was found for employment in furniture and home furnishing stores, and a borderline significantly increased risk among textile sewing machine operators and tenders.
Conclusions:
Working in several occupations and industries was associated with an increased risk of pancreatic cancer in this study, and these associations warrant further investigation.
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