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Updated: Aug 18, 2026

Thrombus Profiling Assay: A Microfluidics-Based Platform for Comprehensively Characterizing Biomechanical Thrombogenesis
Published on: January 9, 2026
[Markers of thrombophilia in patients with retinal vein thrombosis]
Leonidas Traipe1, Guillermo Conte, Francisco J Conte
1Servicio de Oftalmología, Hospital Clínico de la Universidad de Chile, Chile. ltraipe@entelchile.net
Background:
Thrombophilia is an alteration of hemostasis that increases the risk to venous or arterial thrombosis. This condition may be the underlying cause of retinal vein thrombosis.
Aim:
To study the presence of thrombophilia in patients with retinal vein thrombosis.
Patients And Methods:
Prospective study of 55 patients aged 22 to 86 years, with retinal vein thrombosis (central or branch). Antithrombin III, coagulant protein C, functional protein S, resistance to activated C protein, homocysteine, prothrombin G20210A gene, lupus anticoagulant and anticardiolipin antibodies were measured in all.
Results:
Seventeen patients had thrombophilic markers (antiphospholipid syndrome in seven, hyperhomocysteinemia in six and resistance to protein C in three). Of these 17 patients, 53% had high blood pressure, 35% an abnormal serum lipid profile and 23% a personal history of thrombosis. The thrombosis was central in 12 (ischemic in four) and of a branch in five (ischemic in two).
Conclusions:
Thrombophilic markers must be assessed in patients with retinal vein thrombosis.
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Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Venous Thrombosis I: Introduction
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