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Depression in children and adolescents with cystic fibrosis: case studies

Larissa Elgudin1, Sunil Kishan, Don Howe

  • 1University Hospitals of Cleveland, Ohio, USA. laraelg@hotmail.com

International Journal of Psychiatry in Medicine
|April 14, 2005
PubMed

Insights

Antidepressant medications may improve psychological outcomes for children and adolescents with cystic fibrosis (CF). Further clinical studies are needed to confirm the efficacy and safety of these treatments in CF patients.

Area of Science:

  • Medical Research
  • Pediatric Health
  • Psychiatry

Background:

  • Cystic fibrosis (CF) is a genetic disorder affecting multiple systems, notably airways.
  • While CF treatments have improved life expectancy, psychological support remains limited.
  • CF significantly impacts patients' and families' quality of life.

Observation:

  • This study presents three pediatric cases of cystic fibrosis (CF) patients diagnosed with depression.
  • Treatment involved a combination of antidepressant medications and psychosocial interventions.
  • Two out of three patients showed positive psychological outcomes.

Findings:

  • Antidepressant medication, alongside psychosocial interventions, appears beneficial for depression in pediatric CF.
  • The findings suggest a positive influence of antidepressants on psychological well-being in this population.

Implications:

  • Further clinical trials are warranted to establish the efficacy and safety of antidepressants in CF.
  • This research highlights the need for integrated mental health care in cystic fibrosis management.
  • Future studies should assess long-term effects and optimal dosing for CF patients.
Abstract

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