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[Intra-abdominal mycoses].

C Boos1, P Kujath, H-P Bruch

  • 1Klinik für Orthopädie, Universitätsklimikum Schleswig-Holstein-Campus Lübeck, Lübeck, Germany. carsten.boos@netsuf.de

Mycoses
|April 14, 2005
PubMed
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Invasive mycoses, primarily Candida infections, affect 8% of abdominal surgery patients, with a high 60% mortality rate. Early diagnosis and treatment are crucial for survival.

Area of Science:

  • Medical Mycology
  • Surgical Infections
  • Epidemiology

Background:

  • Invasive mycoses are a growing concern in abdominal surgery patients, with an incidence of approximately 8%.
  • Systemic mycoses, predominantly Candida infections, carry a high lethality rate of up to 60%.
  • Risk factors include exogenous, endogenous, and iatrogenic elements, leading to tissue invasion or fungal sepsis.

Purpose of the Study:

  • To review the incidence, characteristics, and management of invasive mycoses in abdominal surgery.
  • To highlight the diagnostic challenges and therapeutic strategies for systemic fungal infections.
  • To emphasize the importance of early diagnosis and intervention to reduce mortality.

Main Methods:

  • Review of epidemiological data on invasive mycoses in abdominal surgery.

Related Experiment Videos

  • Analysis of causative fungal species, with Candida spp. being predominant.
  • Discussion of diagnostic methods including histological and cultural findings.
  • Evaluation of treatment strategies, including antimycotic therapy and surgical intervention.

    • Main Results:

    • Candida species account for the majority of fungal peritonitis cases (70% Candida albicans).
    • Aspergillus species are rarely found in abdominal infections.
    • Histological verification is a key diagnostic criterion for invasive mycosis.
    • Effective management requires timely antimycotic therapy and surgical eradication of infection foci.

    Conclusions:

    • Invasive mycoses pose a significant threat in abdominal surgery, necessitating prompt diagnosis and treatment.
    • Multifaceted treatment approaches, combining antifungal agents and surgery, are essential.
    • Monitoring antimycotic therapy effectiveness through histological assessment aids in optimizing treatment and preventing resistance.