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Gene flow in the Pleistocene.

F B Livingstone1

  • 1Department of Anthropology, University of Michigan, Ann Arbor 48109.

Human Biology
|February 1, 1992
PubMed
Summary
This summary is machine-generated.

Gene flow

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Area of Science:

  • Human evolution
  • Population genetics

Background:

  • Previous models of gene dispersal supported multiregional and single origin theories of human evolution.
  • Estimates by Weiss and Maruyama (1976) and Rouhani (1989) informed these theories.

Purpose of the Study:

  • To re-evaluate gene dispersal times in Pleistocene hominid populations.
  • To assess the role of gene flow versus mutation in human origins.

Main Methods:

  • Computer simulations of gene dispersal.
  • Incorporation of mutation rates and long-range gene flow.

Main Results:

  • Simulations suggest dispersal in 80,000 years with gene flow.
  • However, new advantageous mutations arise more frequently than previously thought.
  • The original advantageous mutant may not disperse before new ones appear.

Conclusions:

  • The role of gene flow in maintaining species may be overstated.
  • Mutation dynamics are critical in understanding human origins.
  • Revisiting the balance between gene flow and mutation is essential.