Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Obstetrical anaesthesia and porphyrias].

D Consolo1, Y Ouardirhi, C Wessels

  • 1Département d'anesthésie-réanimation, CHU le Bocage, 2, boulevard Maréchal-de-Lattre-de-Tassigny, 21000 Dijon, France. djconsolo@yahoo.fr

Annales Francaises D'Anesthesie Et De Reanimation
|April 14, 2005
PubMed
Summary

Managing acute hepatic porphyria (AHP) during delivery requires tailored anesthesia. Asymptomatic patients may use spinal anesthesia, while symptomatic patients benefit from general anesthesia with propofol.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of a shared decision-making tool for systemic treatment in psoriasis.

Annales de dermatologie et de venereologie·2026
Same author

Impact of excess weight on clinical features of psoriasis and efficacy of biologic therapies in children with severe psoriasis: Analysis of data from the BiPe cohorts.

Annales de dermatologie et de venereologie·2025
Same author

Acrodermatitis continua of Hallopeau successfully treated with spesolimab.

Annales de dermatologie et de venereologie·2025
Same author

Methotrexate in monotherapy or combined with oral steroids for bullous pemphigoid in a real-life setting: A retrospective monocentric cohort.

Annales de dermatologie et de venereologie·2025
Same author

Oesophageal lichen planus: Clinical, endoscopic and fibroscopic characteristics.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024
Same author

Treatment of moderate-to-severe psoriasis in adults: An expert consensus statement using a Delphi method to produce a decision-making algorithm.

Annales de dermatologie et de venereologie·2024

Area of Science:

  • Anesthesiology
  • Genetics
  • Obstetrics

Background:

  • Acute hepatic porphyrias (AHP) are genetic disorders presenting with neurological symptoms, often triggered by anesthesia and pregnancy.
  • Safe management of AHP patients during labor and delivery is critical due to potential fatal complications.

Observation:

  • This report details the delivery management of three patients with porphyria.
  • Management strategies were developed through multidisciplinary discussions involving anesthesiologists, obstetricians, and porphyria specialists.

Findings:

  • Asymptomatic or stable AHP patients can safely undergo labor analgesia and Cesarean delivery using locoregional anesthesia (spinal anesthesia with bupivacaine) due to lower anesthetic requirements.
  • Symptomatic AHP patients or those in crisis require intravenous narcotics for labor analgesia and general anesthesia, with propofol as the preferred agent for induction and maintenance.

Related Experiment Videos

Implications:

  • Establishes distinct anesthetic management protocols for AHP patients based on their clinical status (asymptomatic vs. symptomatic).
  • Highlights the importance of propofol as a safe hypnotic agent for AHP patients requiring general anesthesia.
  • Provides a framework for optimizing obstetric and anesthetic care for pregnant individuals with acute hepatic porphyrias.