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Ma huang associated acute liver failure requiring liver transplantation

Ferdinandos Skoulidis¹, Graeme J M Alexander, Susan E Davies

¹Addenbrooke's Hospital, Cambridge, UK.

European Journal of Gastroenterology & Hepatology

|April 14, 2005

Abstract:

An ever increasing number of herbal remedies are recognized as potentially hepatotoxic. We report a case of fulminant hepatic failure requiring liver transplantation associated with the use of Ma huang, a traditional Chinese remedy containing ephedrine-type alkaloids. The literature surrounding the potential liver toxicities of Ma huang is reviewed and the proposed pathogenetic mechanisms are critically examined.

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