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Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Predictors of internalizing symptoms among very low birth weight young women
Maureen Hack1, Eric A Youngstrom, Lydia Cartar
1Department of Pediatrics, Case Western Reserve University, Cleveland, OH 44106, USA. mxh7@cwru.edu
Insights
Very low birth weight may predict internalizing symptoms in young women, particularly white individuals with maternal psychological distress. Childhood IQ and family expressiveness also played a role.
Area of Science:
- Developmental Psychology
- Perinatal Health
- Mental Health Outcomes
Background:
- Longitudinal studies track outcomes of very low birth weight (VLBW) children.
- Internalizing symptoms can manifest in young adulthood.
- Understanding predictors of psychopathology is crucial for early intervention.
Purpose of the Study:
- To identify perinatal, childhood, and young adult predictors of internalizing symptoms.
- To compare VLBW young women with normal birth weight controls.
- To explore factors influencing mental health trajectories from birth to adulthood.
Main Methods:
- Longitudinal cohort study of VLBW and normal birth weight 20-year-olds.
- Stepwise multivariate analyses to examine predictors.
- Data collected on perinatal, childhood, and young adult factors.
Main Results:
- VLBW was a predictor of parent-reported internalizing symptoms in white daughters of mothers with high psychological distress.
- Childhood IQ, prior internalizing symptoms, and family expressiveness predicted young adult internalizing symptoms.
- Asthma history and violence exposure predicted self-reported internalizing symptoms.
Conclusions:
- VLBW's impact on internalizing symptoms is complex and influenced by maternal and familial factors.
- Perinatal risk factors were not direct predictors of 20-year internalizing symptoms.
- Further research into neonatal intensive care's social/environmental factors is needed to explain VLBW's psychopathology link.
Abstract:
As part of a longitudinal study of the outcomes of very low birth weight children (<1.5 kg), we sought to examine the perinatal, childhood, and young adult predictors of internalizing symptoms among very low birth weight young women and their normal birth weight controls. The cohort included 125 very low birth weight and 124 normal birth weight 20-year-old subjects. Perinatal, childhood, and young adult predictors were examined via stepwise multivariate analyses. Results revealed very low birth weight to be a significant predictor of parent-reported internalizing symptoms of their daughters but only among white subjects who had mothers with high levels of psychological distress. Additional significant predictors of 20-year internalizing symptoms included child I.Q. and internalizing symptoms at age 8 years and family expressiveness. When the results were analyzed according to the young adult self-report, additional predictors of internalizing symptoms included a history of asthma and exposure to violence. Perinatal risk factors were not found to be predictive of internalizing symptoms at age 20 years. Future studies should prospectively examine social and environmental factors associated with the neonatal intensive care experience that might explain the effect of very low birth weight on later psychopathology.
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