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Tuberculosis post-liver transplantation: a rare but complicated disease
1Liver Transplant Programme, National University Hospital, Singapore.
Introduction:
Tuberculosis is a rare but serious complication after transplantation. We report a case and discuss its presentation and management.
Clinical Picture:
A 60-year-old Indonesian male presented initially with fever, acute confusion and rapidly progressive right upper lobe pneumonia 3.5 months post-liver transplant, and was diagnosed with pulmonary tuberculosis by positive sputum smear for acid-fast bacilli and tuberculosis culture.
Treatment/Outcome:
Standard anti-tuberculosis therapy was administered but was complicated by interaction with cyclosporine and drug-induced cholestasis.
Conclusion:
A high level of suspicion, prompt antituberculosis treatment and close follow-up are essential in management of post-transplant tuberculosis.
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